Name: Tesamorelin 20mg
Brand: Hati Peptides
SKU: TESA-20MG
Price: 58.5 GBP
Availability: OutOfStock

Question 1

What is Tesamorelin and how does it work in research models?

Accepted Answer

Tesamorelin is a synthetic 44-amino-acid peptide analogue of human growth hormone-releasing hormone (GHRH). In research models, it stimulates endogenous growth hormone secretion through activation of the GHRH receptor in the anterior pituitary. The peptide is based on native GHRH(1-44) with a trans-3-hexenoic acid modification at the N-terminus that protects against degradation and extends half-life. Researchers use tesamorelin to study GHRH receptor pharmacology, GH secretion patterns, and the metabolic effects of the GH-IGF-1 axis.

Question 2

How do I reconstitute Tesamorelin for laboratory use?

Accepted Answer

Reconstitute lyophilised Tesamorelin with bacteriostatic water (0.9% benzyl alcohol). Inject the water slowly down the inside wall of the vial and allow it to flow over the powder. Gently swirl to aid dissolution. Typical research stock concentrations range from 1–10 mg/mL. The peptide is generally soluble in aqueous solutions. Store lyophilised powder at −20°C; reconstituted solution at 2–8°C, protected from light. Solutions are stable for 7–14 days under refrigeration. Avoid repeated freeze-thaw cycles.

Question 3

What purity standard is recommended for Tesamorelin research?

Accepted Answer

Research-grade Tesamorelin should be ≥98% pure by HPLC, with ≥99% being the preferred standard. Mass spectrometry identity confirmation is essential to verify the 44-amino-acid sequence and N-terminal modification. The trans-3-hexenoic acid modification should be confirmed by mass spectrometry (molecular weight shift). Batch-specific Certificates of Analysis should document purity, identity, and endotoxin levels. The N-terminal modification is critical for stability and must be verified analytically.

Question 4

Is Tesamorelin legal for research in the UK?

Accepted Answer

Yes. Tesamorelin is not a controlled substance under the UK Misuse of Drugs Act 1971 and is not scheduled under the Psychoactive Substances Act 2016. It is classified as a research peptide for laboratory use and is not licensed as a medicine by the MHRA. Research institutions should ensure compliance with institutional ethics approvals and standard laboratory safety protocols.

Question 5

What cellular models are used for Tesamorelin research?

Accepted Answer

Standard cellular models include: (1) primary pituitary cells and GH3 cells for GH secretion studies; (2) 3T3-L1 adipocytes for lipolysis and adipokine studies; (3) primary hepatocytes for IGF-1 production and hepatic metabolism; (4) C2C12 myotubes for protein synthesis and muscle metabolism; and (5) transfected cell lines expressing GHRH receptors for binding studies. Researchers compare tesamorelin to GHRPs and direct GH treatment to examine receptor-specific effects.

Tesamorelin 20mg

Research Overview

Areas of Interest

Technical Specifications

Certificate of Analysis