TB-500

TB-500 (Thymosin β-4 fragment) is a synthetic peptide fragment corresponding to a portion of thymosin β-4, an endogenous actin-sequestering protein involved in cellular motility, tissue remodelling, and wound repair. It has been investigated in research models focused on regenerative and tissue-repair pathways.

Areas of Interest

Laboratory studies of TB-500 have investigated a variety of promising areas:

• •Tissue repair & wound healing — studied in preclinical models of dermal and soft-tissue repair for effects on cell migration and tissue remodelling.
• •Actin sequestration & cell motility — investigated for its mechanistic role in G-actin sequestration and implications for cytoskeletal dynamics in research models.
• •Angiogenesis research — explored for effects on vascularisation and endothelial cell migration in wound-healing research models.
• •Inflammation & cytokine modulation — studied for regulatory effects on inflammatory pathways and cytokine expression in research settings.
• •Cardiac & muscle injury models — examined in experimental models of cardiac and skeletal muscle injury for potential regenerative effects.

As a research-grade reference material, our TB-500 is supplied as a lyophilized powder with a purity of ≥98.7% as verified by HPLC and mass spectrometry. Each batch is accompanied by a Certificate of Analysis documenting sequence integrity, molecular weight confirmation, and chromatographic purity.